Squalane

Modify Date: 2024-01-01 17:55:03

Squalane Structure
Squalane structure
 Common Name Squalane
CAS Number 111-01-3 Molecular Weight 422.813
Density 0.8±0.1 g/cm3 Boiling Point 470.3±0.0 °C at 760 mmHg
Molecular Formula C30H62 Melting Point −38 °C(lit.)
MSDS Chinese USA Flash Point 217.8±0.0 °C

 Use of Squalane


Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1].

 Names

Name 2,6,10,15,19,23-hexamethyltetracosane
Synonym More Synonyms

 Squalane Biological Activity

Description Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1].
Related Catalog
In Vitro Squalane exhibits a huge potential in nutraceutical and pharmaceutical industries. Squalane shows anticancer, antioxidant, drug carrier, detoxifier, skin hydrating, and emollient activities have been reported both in animal models and in vitro environments[1].
References

[1]. Kim SK, et al. Biological importance and applications of squalene and squalane. Adv Food Nutr Res. 2012;65:223-33.

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 470.3±0.0 °C at 760 mmHg
Melting Point −38 °C(lit.)
Molecular Formula C30H62
Molecular Weight 422.813
Flash Point 217.8±0.0 °C
Exact Mass 422.485138
LogP 15.59
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.448
Stability Stable. Combustible. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XB6070000
CHEMICAL NAME :
Tetracosane, 2,6,10,15,19,23-hexamethyl-
CAS REGISTRY NUMBER :
111-01-3
BEILSTEIN REFERENCE NO. :
0776019
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C30-H62
MOLECULAR WEIGHT :
422.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84063 No. of Facilities: 109 (estimated) No. of Industries: 3 No. of Occupations: 10 No. of Employees: 20918 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84063 No. of Facilities: 1980 (estimated) No. of Industries: 11 No. of Occupations: 32 No. of Employees: 149812 (estimated) No. of Female Employees: 126648 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS XB6070000
HS Code 2901100000

 Synthetic Route

 Customs

HS Code 2901100000
Summary 2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

 Articles27

More Articles
Biological importance and applications of squalene and squalane.

Adv. Food Nutr. Res. 65 , 223-33, (2012)

Squalene is a polyunsaturated hydrocarbon with a formula of C₃₀H₅₀. Squalene can be found in certain fish oils, especially shark liver oil, in high amounts and some vegetable oils in relatively smalle...

How membrane permeation is affected by donor delivery solvent.

Phys. Chem. Chem. Phys. 14(44) , 15525-38, (2012)

We investigate theoretically and experimentally how the rate and extent of membrane permeation is affected by switching the donor delivery solvent from water to squalane for different permeants and me...

Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model.

J. Oleo Sci. 62(1) , 21-8, (2013)

Active oxygen has been implicated in the pathogenesis of Parkinson's disease (PD); therefore, antioxidants have attracted attention as a potential way to prevent this disease. Squalene, a natural trit...

 Synonyms

Squalane
Robane
Cosbiol
Perhydrosqualene
2,6,10,15,19,23-hexamethylteracosane
Spinacane
2,6,10,15,19,23-Hexamethyltetracosane
Dodecahydrosqualene
2,6,10,15,19,23-Hexamethyltetracosane,Cosbiol,Perhydrosqualene
Vitabiosol
MFCD00008953
Hexamethyltetracosane
EINECS 203-825-6
Tetracosane, 2,6,10,15,19,23-hexamethyl-
poly(ethylenepropylene)
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Chemsrc provides Squalane(CAS#:111-01-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Squalane are included as well.>> amp version: Squalane

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