Adenanthin

Modify Date: 2024-01-05 11:03:16

Adenanthin structure	Common Name	Adenanthin
	CAS Number	111917-59-0	Molecular Weight	490.543
	Density	1.3±0.1 g/cm3	Boiling Point	593.4±50.0 °C at 760 mmHg
	Molecular Formula	C₂₆H₃₄O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	192.6±23.6 °C

Use of Adenanthin

Adenanthin is an inhibitor of thiol-dependent antioxidant enzymes, targeting to Prx 1 and Prx 2. Adenanthin impairs human natural killer (NK) cells effector functions, and killing hepatocellular carcinoma cells. Adenanthin inhibits NF-κB signaling and lipogenesis and the development of obesity by regulating ROS[1].

Name	(1α,3β,5β,7β,8α,9β,10α,11β)-3-Hydroxy-6,15-dioxokaur-16-ene-1,7,1 1-triyl triacetate
Synonym	More Synonyms

Description	Adenanthin is an inhibitor of thiol-dependent antioxidant enzymes, targeting to Prx 1 and Prx 2. Adenanthin impairs human natural killer (NK) cells effector functions, and killing hepatocellular carcinoma cells. Adenanthin inhibits NF-κB signaling and lipogenesis and the development of obesity by regulating ROS[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	Prx 1, Prx 2, NF-κB[1]
References	[1]. Hu J, et al. Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS. Molecules. 2019 Jan 3;24(1):158.

Density	1.3±0.1 g/cm3
Boiling Point	593.4±50.0 °C at 760 mmHg
Molecular Formula	C₂₆H₃₄O₉
Molecular Weight	490.543
Flash Point	192.6±23.6 °C
Exact Mass	490.220276
PSA	133.27000
LogP	1.36
Vapour Pressure	0.0±3.8 mmHg at 25°C
Index of Refraction	1.550