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  • BioBioPha
  • China
  • Product Name: Adenanthin
  • Price: ¥5000.0/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng



111917-59-0

111917-59-0 structure
111917-59-0 structure
  • Name: Adenanthin
  • Chemical Name: (1α,3β,5β,7β,8α,9β,10α,11β)-3-Hydroxy-6,15-dioxokaur-16-ene-1,7,1 1-triyl triacetate
  • CAS Number: 111917-59-0
  • Molecular Formula: C26H34O9
  • Molecular Weight: 490.543
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2017-09-17 07:05:31
  • Modify Date: 2024-01-05 11:03:16
  • Adenanthin is an inhibitor of thiol-dependent antioxidant enzymes, targeting to Prx 1 and Prx 2. Adenanthin impairs human natural killer (NK) cells effector functions, and killing hepatocellular carcinoma cells. Adenanthin inhibits NF-κB signaling and lipogenesis and the development of obesity by regulating ROS[1].

Name (1α,3β,5β,7β,8α,9β,10α,11β)-3-Hydroxy-6,15-dioxokaur-16-ene-1,7,1 1-triyl triacetate
Synonyms (1α,3β,5β,7β,8α,9β,10α,11β)-3-Hydroxy-6,15-dioxokaur-16-ene-1,7,11-triyl triacetate
Description Adenanthin is an inhibitor of thiol-dependent antioxidant enzymes, targeting to Prx 1 and Prx 2. Adenanthin impairs human natural killer (NK) cells effector functions, and killing hepatocellular carcinoma cells. Adenanthin inhibits NF-κB signaling and lipogenesis and the development of obesity by regulating ROS[1].
Related Catalog
Target

Prx 1, Prx 2, NF-κB[1]

References

[1]. Hu J, et al. Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS. Molecules. 2019 Jan 3;24(1):158.  

Density 1.3±0.1 g/cm3
Boiling Point 593.4±50.0 °C at 760 mmHg
Molecular Formula C26H34O9
Molecular Weight 490.543
Flash Point 192.6±23.6 °C
Exact Mass 490.220276
PSA 133.27000
LogP 1.36
Vapour Pressure 0.0±3.8 mmHg at 25°C
Index of Refraction 1.550
Hazard Codes Xi