Dexanabinol
Dexanabinol structure
|
Common Name | Dexanabinol | ||
|---|---|---|---|---|
| CAS Number | 112924-45-5 | Molecular Weight | 386.567 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 470.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C25H38O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 238.1±28.7 °C | |
Use of DexanabinolDexanabinol (HU-211) is an artificially synthesized cannabinoid derivative and lacks cannabimimetic effects. Dexanabinol exhibits not only the antioxidant and neuroprotective activities in brain but also anti-inflammatory activity by inhibiting NF-κB and decreasing cytokines such as TNFα and interleukin-6, which could ensure the integrity of BBB and reduce cell apoptosis and death. Dexanabinol is widely used in head injury or stroke treatment and has been shown to be safe in animals and humans[1]. |
| Name | (6aS,10aS)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol |
|---|---|
| Synonym | More Synonyms |
| Description | Dexanabinol (HU-211) is an artificially synthesized cannabinoid derivative and lacks cannabimimetic effects. Dexanabinol exhibits not only the antioxidant and neuroprotective activities in brain but also anti-inflammatory activity by inhibiting NF-κB and decreasing cytokines such as TNFα and interleukin-6, which could ensure the integrity of BBB and reduce cell apoptosis and death. Dexanabinol is widely used in head injury or stroke treatment and has been shown to be safe in animals and humans[1]. |
|---|---|
| Related Catalog | |
| Target |
NF-κB TNFα IL-6 |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 470.1±45.0 °C at 760 mmHg |
| Molecular Formula | C25H38O3 |
| Molecular Weight | 386.567 |
| Flash Point | 238.1±28.7 °C |
| Exact Mass | 386.282104 |
| PSA | 49.69000 |
| LogP | 8.19 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.526 |
|
~98%
Dexanabinol CAS#:112924-45-5 |
| Literature: Tetrahedron: Asymmetry, , vol. 1, # 5 p. 315 - 318 |
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~%
Dexanabinol CAS#:112924-45-5 |
| Literature: Tetrahedron: Asymmetry, , vol. 1, # 5 p. 315 - 318 |
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~%
Dexanabinol CAS#:112924-45-5 |
| Literature: Tetrahedron: Asymmetry, , vol. 1, # 5 p. 315 - 318 |
|
~%
Dexanabinol CAS#:112924-45-5 |
| Literature: Tetrahedron: Asymmetry, , vol. 1, # 5 p. 315 - 318 |
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~%
Dexanabinol CAS#:112924-45-5 |
| Literature: Tetrahedron: Asymmetry, , vol. 1, # 5 p. 315 - 318 |
|
~%
Dexanabinol CAS#:112924-45-5 |
| Literature: Tetrahedron: Asymmetry, , vol. 1, # 5 p. 315 - 318 |
![((1S,5R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl pivalate structure](https://image.chemsrc.com/caspic/208/113473-31-7.png)
![2,2-DIMETHYL-PROPIONIC ACID (1R,5R)-4-HYDROXY-6,6-DIMETHYL-BICYCLO[3.1.1]HEPT-2-EN-2-YLMETHYL ESTER structure](https://image.chemsrc.com/caspic/175/76163-97-8.png)
![2,2-DIMETHYL-PROPIONIC ACID (1R,5R)-6,6-DIMETHYL-4-OXO-BICYCLO[3.1.1]HEPT-2-EN-2-YLMETHYL ESTER structure](https://image.chemsrc.com/caspic/213/76163-96-7.png)
| 6H-Dibenzo[b,d]pyran-9-methanol, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-, (6aS,10aS)- |
| (6aS,10aS)-9-(Hydroxymethyl)-6,6-dimethyl-3-(2-methyl-2-octanyl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol |
| (6aS,10aS)-9-(Hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol |
| Sinnabidiol |
| 1,1-Dimethylheptyl-11-hydroxytetrahydrocannabinol |
| HU-211 |
| Dexanabinol |