4-Fluoro-Phe-OH

Modify Date: 2024-01-01 20:49:09

4-Fluoro-Phe-OH Structure
4-Fluoro-Phe-OH structure
Common Name 4-Fluoro-Phe-OH
CAS Number 1132-68-9 Molecular Weight 183.180
Density 1.3±0.1 g/cm3 Boiling Point 313.3±32.0 °C at 760 mmHg
Molecular Formula C9H10FNO2 Melting Point ~255 °C (dec.)
MSDS Chinese USA Flash Point 143.3±25.1 °C

 Use of 4-Fluoro-Phe-OH


p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli (KD=0.26 μM)[1][2].

 Names

Name 4-fluorophenyl-L-alanine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 313.3±32.0 °C at 760 mmHg
Melting Point ~255 °C (dec.)
Molecular Formula C9H10FNO2
Molecular Weight 183.180
Flash Point 143.3±25.1 °C
Exact Mass 183.069550
PSA 63.32000
LogP 1.16
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.555

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S23-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DW1765000

 Synthetic Route

 Articles5

More Articles
Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Regulation of rat liver phenylalanine hydroxylase. I. Kinetic properties of the enzyme's iron and enzyme reduction site.

J. Biol. Chem. 269 , 24637, (1994)

Tetrahydropterins react with phenylalanine hydroxylase at a redox site, a regulatory site, and the catalytic site, but neither the properties of nor relationships among these sites are well understood...

 Synonyms

L-4-FLUOROPHE
(2R)-2-Amino-3-(4-fluorophenyl)propanoic acid
D,L-p-fluorophenylalanine
L-4-F-Phe-OH
L-p-fluorophenylalanine
4-Fluorophenylalanine
H-Phe(4-F)-OH
H-L-PHE(4-F)-OH
L-4-Fluorophenylalanine
4-fluoroPhe
RARECHEM BK PT 0031
(2R)-2-amino-3-(4-fluorophenyl)propionic acid
D-4-Fluorophenylalanine
Phenylalanine, 4-fluoro-
para-fluoro-l-phenylalanine
H-PHE(P-F)-OH
D-4-Fluorophe
H-P-FLUORO-PHE-OH
(S)-2-Amino-3-(4-fluorophenyl)propanoic acid
4-Fluoro-Phe-OH
MFCD00063064
S-(-)-p-Fluorophenylalanine
para-fluorophenylalanine
p-Fluoro-L-phenylalanine
L-4-Fluoro-Phenylalanine
D,L-4-fluorophenylalanine
L-4-Fluoro-phe-OH
(2S)-2-amino-3-(4-fluorophenyl)propanoic acid
H-D-Phe(4-F)-OH
(S)-4-Fluorophenylalanine
4-Fluoro-L-phenylalanine
(S)-2-Amino-3-(4-fluorophenyl)propionic Acid
4-FLUOROPHENYLALANINE, D-
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