2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID

Modify Date: 2024-01-01 18:00:40

2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID structure	Common Name	2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID
	CAS Number	113919-36-1	Molecular Weight	224.15200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆H₁₃N₂O₅P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID

PMPA (NMDA antagonist) is an NMDA receptor antagonist with Ki values of 0.84, 2.74, 3.53 and 4.16 μM for NR2A, NR2B, NR2C and NR2D, respectively[1].

Name	4-(phosphonomethyl)piperazine-2-carboxylic acid

Description	PMPA (NMDA antagonist) is an NMDA receptor antagonist with Ki values of 0.84, 2.74, 3.53 and 4.16 μM for NR2A, NR2B, NR2C and NR2D, respectively[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	Ki: 0.84 μM (NR2A), 2.74 μM (NR2B), 3.53 μM (NR2C), 4.16 μM (NR2D)[1]
References	[1]. Feng B, et al. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology. 2005 Mar;48(3):354-9.

Molecular Formula	C₆H₁₃N₂O₅P
Molecular Weight	224.15200
Exact Mass	224.05600
PSA	119.91000

2-methyl 1-phenylmethyl 1,2-piperazinedicarboxilate, trifluoroacetate structure

2-methyl 1-phen...

CAS#:126937-44-8

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2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID Structure

2-(PHOSPHONOMET...

CAS#:113919-36-1

Literature: Hays; Bigge; Novak; Drummond; Bobovski; Rice; Johnson; Brahce; Coughenour Journal of Medicinal Chemistry, 1990 , vol. 33, # 10 p. 2916 - 2924

Precursor 1
CAS#:126937-44-8 2-methyl 1-phen...
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Dayang Chem (Hangzhou) Co., Ltd.
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