Clopidogrel thiolactone

Modify Date: 2024-01-03 06:36:56

Clopidogrel thiolactone Structure
Clopidogrel thiolactone structure
Common Name Clopidogrel thiolactone
CAS Number 1147350-75-1 Molecular Weight 337.821
Density 1.4±0.1 g/cm3 Boiling Point 488.1±45.0 °C at 760 mmHg
Molecular Formula C16H16ClNO3S Melting Point N/A
MSDS N/A Flash Point 249.0±28.7 °C

 Use of Clopidogrel thiolactone


Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent.Target: P2Y12Clopidogrel thiolactone is the metabolic intermediate resulting from the first oxidative activation of clopidogrel.

 Names

Name methyl (2S)-2-(2-chlorophenyl)-2-(2-oxo-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate
Synonym More Synonyms

 Clopidogrel thiolactone Biological Activity

Description Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent.Target: P2Y12Clopidogrel thiolactone is the metabolic intermediate resulting from the first oxidative activation of clopidogrel.
Related Catalog
References

[1]. Shan J, et al. Overcoming Clopidogrel Resistance: Discovery of Vicagrel as a Highly Potent and Orally Bioavailable Antiplatelet Agent

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 488.1±45.0 °C at 760 mmHg
Molecular Formula C16H16ClNO3S
Molecular Weight 337.821
Flash Point 249.0±28.7 °C
Exact Mass 337.053955
PSA 71.91000
LogP 2.96
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.640
Storage condition 2-8℃

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(S)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate
(2S)-Methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate
(2'S)-2-oxo-clopidogrel
[8S]-2-oxo-clopidogrel
clopidogrel thiolactone
Methyl (2S)-(2-chlorophenyl)(2-oxo-2,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
(2S)-methyl 2-(2-oxo-7,7a-dihydrothieno[3,2-c]pyridin-5(2H,4H,6H)-yl)-2-(2-chlorophenyl)acetate
Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-2,6,7,7a-tetrahydro-2-oxo-, methyl ester, (αS)-
2-Oxoclopidogrel
methyl (2'S)-2-(2-chlorophenyl)-2-(2,4,5,6,7,7a-hexahydrothieno[3,2-c]-5-pyridin-2-one)acetate
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