Losartan Carboxaldehyde

Modify Date: 2024-01-08 15:40:52

Losartan Carboxaldehyde structure	Common Name	Losartan Carboxaldehyde
	CAS Number	114798-36-6	Molecular Weight	420.895
	Density	1.3±0.1 g/cm3	Boiling Point	666.7±65.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₁ClN₆O	Melting Point	84-86 °C
	MSDS	N/A	Flash Point	357.0±34.3 °C

Use of Losartan Carboxaldehyde

EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions[1].

Name	2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde
Synonym	More Synonyms

Description	EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
References	[1]. Rossi GP. Losartan metabolite EXP3179: an AT1-receptor-independent treatment strategy for patients with the metabolic syndrome?. Hypertension. 2009;54(4):710-712.

Density	1.3±0.1 g/cm3
Boiling Point	666.7±65.0 °C at 760 mmHg
Melting Point	84-86 °C
Molecular Formula	C₂₂H₂₁ClN₆O
Molecular Weight	420.895
Flash Point	357.0±34.3 °C
Exact Mass	420.146545
PSA	89.35000
LogP	5.09
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.681

Precursor 7
CAS#:124750-67-0 2-n-Butyl-4-chl... CAS#:124750-99-8 Losartan potassium CAS#:18039-42-4 5-Phenyl-1H-tet... CAS#:41882-10-4 N-(4-methoxyben...
CAS#:98-88-4 Benzoyl chloride CAS#:57598-33-1 2-(2-methoxyphe... CAS#:114772-53-1 4'-Methyl-2-cya...
DownStream 1
CAS#:114798-26-4 Losartan

1H-imidazole-5-carboxaldehyde, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-imidazole-5-carbaldehyde

2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carbaldehyde

2-Butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-imidazole-5-carbaldehyde

2-n-Butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-imidazole-5-carboxaldehyde

2-butyl-4-chloro-1-<<2'-(1H-tetrazol-5-yl)biphenyl-4-yl>methyl>imidazole-5-carboxaldehyde

[3H]-EXP 3179

1H-Imidazole-5-carboxaldehyde, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

EXP 3179

2-butyl-4-chloro-5-formyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methylimidazole

Losartan Carboxaldehyde

2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carbaldehyde

2-Butyl-4-chloro-1-[[2 inverted exclamation mark-(1H-tetrazol-5-yl)[1,1 inverted exclamation mark-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

DUP 167

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Losartan Carboxaldehyde
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: EXP3179
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Losartan Carboxaldehyde

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