3,5-Diiodothyropropionic Acid

Modify Date: 2024-01-21 15:42:00

3,5-Diiodothyropropionic Acid Structure
3,5-Diiodothyropropionic Acid structure
Common Name 3,5-Diiodothyropropionic Acid
CAS Number 1158-10-7 Molecular Weight 510.06200
Density 2.068g/cm3 Boiling Point 535.3ºC at 760mmHg
Molecular Formula C15H12I2O4 Melting Point N/A
MSDS N/A Flash Point 277.6ºC

 Use of 3,5-Diiodothyropropionic Acid


3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].

 Names

Name 3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid
Synonym More Synonyms

 3,5-Diiodothyropropionic Acid Biological Activity

Description 3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].
Related Catalog
References

[1]. Pennock GD, et al. Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity. J Pharmacol Exp Ther. 1992 Oct;263(1):163-9.

 Chemical & Physical Properties

Density 2.068g/cm3
Boiling Point 535.3ºC at 760mmHg
Molecular Formula C15H12I2O4
Molecular Weight 510.06200
Flash Point 277.6ºC
Exact Mass 509.88300
PSA 66.76000
LogP 4.41090
Vapour Pressure 2.72E-12mmHg at 25°C
Index of Refraction 1.708

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36/37
HS Code 2918990090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

DITPA
3-[4-(4-hydroxy-phenoxy)-3,5-diiodo-phenyl]-propionic acid
3,5-Ditpa
Dipro
DIPTA
3-[4-(4-Hydroxy-phenoxy)-3,5-dijod-phenyl]-propionsaeure
MFCD00045945
3-<4-(4-Hydroxy-phenoxy)-3,5-diiod-phenyl>-propionsaeure
3,5-Diiod-thyropropionsaeure
3,5-DIIODO-4-(4-HYDROXYPHENOXY)HYDROCINNAMIC ACID
3,5-Diiodothyropropionic acid
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