Benzenesulfonamide,4-amino-N-2-pyrazinyl-

Modify Date: 2024-02-04 08:20:57

Benzenesulfonamide,4-amino-N-2-pyrazinyl- Structure
Benzenesulfonamide,4-amino-N-2-pyrazinyl- structure
Common Name Benzenesulfonamide,4-amino-N-2-pyrazinyl-
CAS Number 116-44-9 Molecular Weight 250.27700
Density 1.496g/cm3 Boiling Point 485.5ºC at 760mmHg
Molecular Formula C10H10N4O2S Melting Point N/A
MSDS N/A Flash Point 247.4ºC

 Names

Name 4-amino-N-pyrazin-2-ylbenzenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.496g/cm3
Boiling Point 485.5ºC at 760mmHg
Molecular Formula C10H10N4O2S
Molecular Weight 250.27700
Flash Point 247.4ºC
Exact Mass 250.05200
PSA 106.35000
LogP 2.59460
Vapour Pressure 1.41E-09mmHg at 25°C
Index of Refraction 1.679

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DA9550000
CHEMICAL NAME :
Benzenesulfonamide, 4-amino-N-pyrazinyl-
CAS REGISTRY NUMBER :
116-44-9
BEILSTEIN REFERENCE NO. :
0235481
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C10-H10-N4-O2-S
MOLECULAR WEIGHT :
250.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
45600 mg/kg/22W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes Endocrine - thyroid weight (goiter) Related to Chronic Data - death
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
45 gm/kg/90D-C
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943

 Safety Information

HS Code 2935009090

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

SULFAPYRAZINE
4-amino-N-pyrazin-2-yl-benzenesulfonamide
2-Sulfanilamidopyrazine
sulfanilic acid pyrazin-2-ylamide
N(sup 1)-2-Pyrazinylsulfonilamide
Sulfanilamide,N1-(pyrazinyl)
Benzenesulfonamide,4-amino-N-pyrazinyl
Sulfanilsaeure-pyrazin-2-ylamid
Pyrazine,sulfanilamido
N1-2-Pyrazinylsulfanilamide
4-amino-N-2-pyrazinylbenzenesulfonamide
4-amino-N-pyrazinyl-benzenesulfonamide
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