2-Chloropyrazine

Modify Date: 2024-01-02 16:38:30

2-Chloropyrazine Structure
2-Chloropyrazine structure
Common Name 2-Chloropyrazine
CAS Number 14508-49-7 Molecular Weight 114.533
Density 1.3±0.1 g/cm3 Boiling Point 155.3±20.0 °C at 760 mmHg
Molecular Formula C4H3ClN2 Melting Point N/A
MSDS Chinese USA Flash Point 57.8±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Use of 2-Chloropyrazine


Chloropyrazine (Pyrazin-2-yl chloride) is a member of pyrazines, can be used for the synthesis of active compounds[1].

 Names

Name 2-Chloropyrazine
Synonym More Synonyms

 2-Chloropyrazine Biological Activity

Description Chloropyrazine (Pyrazin-2-yl chloride) is a member of pyrazines, can be used for the synthesis of active compounds[1].
Related Catalog
References

[1]. Mosrin M, et al. Regio- and chemoselective multiple functionalization of chloropyrazine derivatives. Application to the synthesis of coelenterazine. Org Lett. 2009 Aug 6;11(15):3406-9.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 155.3±20.0 °C at 760 mmHg
Molecular Formula C4H3ClN2
Molecular Weight 114.533
Flash Point 57.8±0.0 °C
Exact Mass 113.998474
PSA 25.78000
LogP 0.64
Vapour Pressure 3.9±0.3 mmHg at 25°C
Index of Refraction 1.535
Water Solubility INSOLUBLE

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR UN 1993 3/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 3
HS Code 29339990

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles2

More Articles
Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine.

J. Org. Chem. 74(8) , 3221-4, (2009)

A cobalt-catalyzed cross-coupling of aryl halides with 2-chloropyrimidines or 2-chloropyrazines is reported in satisfactory to high yields. The key step of this procedure is the formation of aromatic ...

Gas chromatographic assay for the new antitumor agent pyrazine-2-diazohydroxide (diazohydroxide) and its stability in buffer, blood and plasma.

J. Chromatogr. A. 383(1) , 77-83, (1986)

Diazohydroxide is a new antitumor agent being considered for clinical trial. A sensitive and specific assay for diazohydroxide in physiological media, plasma and blood has been developed based on conv...

 Synonyms

2-Chloro-pyrazine
2-chloropyrazin
2-Dichloropyrazine
Pyrazine,chloro
Pyrazine, 2-chloro-
2-chloro-1,4-pyrazine
2-Chloro-1,4-diazine
chloro-pyrazin
EINECS 238-517-0
MFCD00006124
Chloropyrazine
pyrazine chloride
2-Cl-pyrazine
CHLOROPYRAZINE,2
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