Sarafotoxin S6b
Modify Date: 2024-01-22 21:06:19
Sarafotoxin S6b structure
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Common Name | Sarafotoxin S6b | ||
|---|---|---|---|---|
| CAS Number | 116303-65-2 | Molecular Weight | 2563.925 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 2570.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C110H159N27O34S5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 1508.1±34.3 °C | |
| Name | Sarafotoxin S6b |
|---|---|
| Synonym | More Synonyms |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 2570.1±65.0 °C at 760 mmHg |
| Molecular Formula | C110H159N27O34S5 |
| Molecular Weight | 2563.925 |
| Flash Point | 1508.1±34.3 °C |
| Exact Mass | 2562.014648 |
| LogP | -3.68 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.563 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Sarafotoxin, a novel vasoconstrictor peptide: phosphoinositide hydrolysis in rat heart and brain.
Science 242 , 268, (1988) Sarafotoxins, a group of 21-residue cardiotoxic peptides from snake venom that induce coronary vasoconstriction, show high-affinity binding to rat atrial and brain membranes and activate the hydrolysi... |
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Sarafotoxins S6: several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart.
Toxicon 26 , 543, (1988) Three isotoxins, named sarafotoxins S6a1, S6b and S6c, with strong cardiotoxic activity were isolated from the venom of a snake, Atractaspis engaddensis. All three sarafotoxins are homologous peptides... |
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Role of the endothelin axis and its antagonists in the treatment of cancer.
Br. J. Pharmacol. 163 , 220-233, (2011) The endothelins (ET) are a group of proteins that act through G-protein coupled receptors. Endothelin-1 (ET-1) was initially identified as a potent vasoconstrictor and dysregulation of the ET axis con... |
| N-({(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-Amino-7,22-bis(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10,19-bis(carboxymethyl)-42-(4-hydroxybenzyl)-13-(1-hydroxyethyl)-28-(hydroxymethyl)-45-isobutyl-16-[2-(methylsulfanyl)ethyl]-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacont-36-yl}carbonyl)-L-histidyl-L-glutaminyl- |
| L-Tryptophan, N-[[(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-7,22-bis(4-aminobutyl)-4-(2-carboxyethyl)-10,19-bis(carboxymethyl)-13-(1-hydroxyethyl)-28-(hydroxymethyl)-42-[(4-hydroxyphenyl)methyl]-45-(2-methylpropyl)-16-[2-(methylthio)ethyl]-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-39-(phenylmethyl)-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacont-36-yl] |
| MFCD00153553 |