120972-53-4

120972-53-4 structure

Name: Sarafotoxin B trifluoroacetate salt
Chemical Name: sarafotoxin s6b
CAS Number: 120972-53-4
Molecular Formula: C₁₁₀H₁₅₉N₂₇O₃₄S₅
Molecular Weight: 2563.92000
Catalog: Signaling Pathways GPCR/G Protein Endothelin Receptor
Create Date: 2019-01-01 20:15:05
Modify Date: 2024-01-05 19:51:29
Sarafotoxin S6b is a vasoconstrictor peptide, and a non-selective endothelin receptor agonist. Sarafotoxin S6b can induce contraction in isolated human coronary arteries , the Ki values of Coronary artery, Saphenous vein and Coronary artery are 0.27, 0.55 and 19.5 nM, respectively[1].

Name	sarafotoxin s6b
Synonyms	CSCKDMTDKECLYFCHQDVIW Sarafotoxin 6b M.W. 2564.00 C110H159N27O34S5 SRTX-B SARAFOTOXIN B

Description	Sarafotoxin S6b is a vasoconstrictor peptide, and a non-selective endothelin receptor agonist. Sarafotoxin S6b can induce contraction in isolated human coronary arteries , the Ki values of Coronary artery, Saphenous vein and Coronary artery are 0.27, 0.55 and 19.5 nM, respectively[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor
References	[1]. P S Devadason et al. Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br J Pharmacol. 1997 May;121(2):253-63.