2H-Pyran-3(6H)-one,2-[[(3b,20S)-20-[(2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-17-hydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-

Modify Date: 2024-04-07 11:26:29

2H-Pyran-3(6H)-one,2-[[(3b,20S)-20-[(2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-17-hydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl- Structure
2H-Pyran-3(6H)-one,2-[[(3b,20S)-20-[(2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-17-hydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl- structure
Common Name 2H-Pyran-3(6H)-one,2-[[(3b,20S)-20-[(2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-17-hydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-
CAS Number 116782-73-1 Molecular Weight 604.77
Density 1.3±0.1 g/cm3 Boiling Point 735.6±60.0 °C at 760 mmHg
Molecular Formula C34H52O9 Melting Point N/A
MSDS N/A Flash Point 227.8±26.4 °C

 Use of 2H-Pyran-3(6H)-one,2-[[(3b,20S)-20-[(2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-17-hydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-


Periplocoside M (compound 8) is a natural product isolated from the root bark of Periploca sepium. Periplocoside M shows antitumor activity against human A-549 and HepG2 cell lines, with the IC50 of 4.84 and 7.06 μM[1].

 Names

Name (3β,20S)-17-Hydroxy-3-{[(2R,6R)-4-methoxy-6-methyl-3-oxo-3,6-dihydro-2H-pyran-2-yl]oxy}pregn-5-en-20-yl 2,6-dideoxy-β-D-arabino-hexopyranoside
Synonym More Synonyms

  Biological Activity

Description Periplocoside M (compound 8) is a natural product isolated from the root bark of Periploca sepium. Periplocoside M shows antitumor activity against human A-549 and HepG2 cell lines, with the IC50 of 4.84 and 7.06 μM[1].
Related Catalog
Target

4.84 μM (A-549 cells) and 7.06 μM (HepG2 cells)[1]

References

[1]. Gu XY, et al. C21 steroidal glycosides and oligosaccharides from the root bark of Periploca sepium. Fitoterapia. 2017;118:6-12.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 735.6±60.0 °C at 760 mmHg
Molecular Formula C34H52O9
Molecular Weight 604.77
Flash Point 227.8±26.4 °C
Exact Mass 604.361145
LogP 4.63
Vapour Pressure 0.0±5.5 mmHg at 25°C
Index of Refraction 1.575

 Synonyms

(3β,20S)-17-Hydroxy-3-{[(2R,6R)-4-methoxy-6-methyl-3-oxo-3,6-dihydro-2H-pyran-2-yl]oxy}pregn-5-en-20-yl 2,6-dideoxy-β-D-arabino-hexopyranoside
2H-Pyran-3(6H)-one, 2-[[(3β,20S)-20-[(2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-17-hydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-, (2R,6R)-