Triptonediol

Modify Date: 2024-03-08 14:35:26

Triptonediol Structure
Triptonediol structure
Common Name Triptonediol
CAS Number 117456-87-8 Molecular Weight 346.46
Density 1.1±0.1 g/cm3 Boiling Point 529.6±50.0 °C at 760 mmHg
Molecular Formula C21H30O4 Melting Point N/A
MSDS N/A Flash Point 183.4±23.6 °C

 Use of Triptonediol


Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK[1][2].

 Names

Name (1S,4aS,10aR)-5-hydroxy-1-(hydroxymethyl)-7-isopropyl-8-methoxy-1,4a-dimethyl-3,4,4a,9,10,10a-hexahydrophenanthren-2(1H)-one
Synonym More Synonyms

 Triptonediol Biological Activity

Description Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK[1][2].
Related Catalog
References

[1]. Zhou BN, et al. Studies on New Components and Stereochemistry of Diterpenoids from Trypterygium wilfordii. Planta Med. 1988 Aug;54(4):330-2.  

[2]. Feng Jin, et al. Network pharmacology‑based investigation of potential targets of Triptonodiol acting on Non-Small-Cell Lung Cancer. Research Square. 2023. DOI: 10.21203/rs.3.rs-2463976/v1

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 529.6±50.0 °C at 760 mmHg
Molecular Formula C21H30O4
Molecular Weight 346.46
Flash Point 183.4±23.6 °C
Exact Mass 346.214417
PSA 66.76000
LogP 3.69
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.546

 Safety Information

Hazard Codes Xi

 Synonyms

11,19-Dihydroxy-14-methoxyabieta-8(14),9(11),12-trien-3-one
Triptonediol
2(1H)-Phenanthrenone, 3,4,4a,9,10,10a-hexahydro-5-hydroxy-1-(hydroxymethyl)-8-methoxy-1,4a-dimethyl-7-(1-methylethyl)-, (1S,4aS,10aR)-