Sodium Taurodeoxycholate

Modify Date: 2024-01-04 12:03:24

Sodium Taurodeoxycholate structure	Common Name	Sodium Taurodeoxycholate
	CAS Number	1180-95-6	Molecular Weight	521.685
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₄NNaO₆S	Melting Point	168 °C (dec.)(lit.)
	MSDS	N/A	Flash Point	N/A

Use of Sodium Taurodeoxycholate

Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses[1] [2][3].

Name	Taurodeoxycholic acid sodium salt hydrate
Synonym	More Synonyms

Description	Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses[1] [2][3].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Villavicencio-Queijeiro A, et al. The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric. J Bioenerg Biomembr. 2009 Feb;41(1):1-13. [2]. Kispal G,et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. J Biol Chem. 1986 Oct 25;261(30):14209-13. [3]. Choi HJ, et al. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats. Drug Chem Toxicol. 2019 Jun 19:1-9.

Description

Related Catalog

Research Areas >> Inflammation/Immunology

References

[1]. Villavicencio-Queijeiro A, et al. The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric. J Bioenerg Biomembr. 2009 Feb;41(1):1-13.

[2]. Kispal G,et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. J Biol Chem. 1986 Oct 25;261(30):14209-13.

[3]. Choi HJ, et al. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats. Drug Chem Toxicol. 2019 Jun 19:1-9.

Melting Point	168 °C (dec.)(lit.)
Molecular Formula	C₂₆H₄₄NNaO₆S
Molecular Weight	521.685
Exact Mass	521.278687
PSA	135.14000
LogP	4.52640
Storage condition	-20℃
Water Solubility	soluble

Hazard Codes	Xi: Irritant;
Risk Phrases	R37
WGK Germany	3

Taurine

CAS#:107-35-7

Deoxycholic acid

CAS#:83-44-3

~95%

Sodium Taurodeo...

CAS#:1180-95-6

Literature: Venturoni, Francesco; Gioiello, Antimo; Sardella, Roccaldo; Natalini, Benedetto; Pellicciari, Roberto Organic and Biomolecular Chemistry, 2012 , vol. 10, # 20 p. 4109 - 4115

Precursor 2
CAS#:107-35-7 Taurine CAS#:83-44-3 Deoxycholic acid
DownStream 2
CAS#:107-35-7 Taurine CAS#:83-44-3 Deoxycholic acid

MFCD00003671

Ethanesulfonic acid, 2-[[(3α,5β,12α,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

Sodium 2-(((3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl)amino)ethane-1-sulphonate

EINECS 214-652-0

Sodium 2-{[(3α,5β,12α,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate

Taurodeoxycholate sodium salt

Sodium Taurodeoxycholate

Taurodeoxycholic acid sodiuM salt

Sodium taurodeoxycholate hydrate

Sodium Taurodeoxycholate

Use of Sodium Taurodeoxycholate

Names

Sodium Taurodeoxycholate Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms