(S)-Lathosterol-d4

Modify Date: 2024-01-03 20:08:40

(S)-Lathosterol-d4 Structure
(S)-Lathosterol-d4 structure
Common Name (S)-Lathosterol-d4
CAS Number 1182005-25-9 Molecular Weight 390.68
Density 1.0±0.1 g/cm3 Boiling Point 479.5±44.0 °C at 760 mmHg
Molecular Formula C27H42D4O Melting Point N/A
MSDS N/A Flash Point 208.9±20.7 °C

 Use of (S)-Lathosterol-d4


(S)-Lathosterol-d4 is the deuterium labeled (S)-Lathosterol. Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis[1].

 Names

Name (5α,6S,9β)-(1,2,5,6-2H4)Cholest-7-en-3-ol
Synonym More Synonyms

 (S)-Lathosterol-d4 Biological Activity

Description (S)-Lathosterol-d4 is the deuterium labeled (S)-Lathosterol. Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis[1].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Kempen HJ, et al. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res. 1988 Sep;29(9):1149-55.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 479.5±44.0 °C at 760 mmHg
Molecular Formula C27H42D4O
Molecular Weight 390.68
Flash Point 208.9±20.7 °C
Exact Mass 390.379974
LogP 9.76
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.525

 Synonyms

(5α,6S,9β)-(1,2,5,6-H)Cholest-7-en-3-ol
Cholest-7-en-1,2,5,6-d-3-ol, (5α,6S,9β)-