1182005-25-9

1182005-25-9 structure

Name: (S)-Lathosterol-d4
Chemical Name: (5α,6S,9β)-(1,2,5,6-2H4)Cholest-7-en-3-ol
CAS Number: 1182005-25-9
Molecular Formula: C₂₇H₄₂D₄O
Molecular Weight: 390.68
Create Date: 2018-04-28 15:53:40
Modify Date: 2024-01-03 20:08:40
(S)-Lathosterol-d4 is the deuterium labeled (S)-Lathosterol. Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis[1].

Name	(5α,6S,9β)-(1,2,5,6-2H4)Cholest-7-en-3-ol
Synonyms	(5α,6S,9β)-(1,2,5,6-H)Cholest-7-en-3-ol Cholest-7-en-1,2,5,6-d-3-ol, (5α,6S,9β)-

Description	(S)-Lathosterol-d4 is the deuterium labeled (S)-Lathosterol. Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis[1].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kempen HJ, et al. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res. 1988 Sep;29(9):1149-55.