BW A868C structure
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Common Name | BW A868C | ||
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CAS Number | 118675-50-6 | Molecular Weight | 459.578 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 638.1±65.0 °C at 760 mmHg | |
Molecular Formula | C25H37N3O5 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 339.7±34.3 °C |
Use of BW A868CBW A868C, a hydantoin compound, is a BW245C structural analogue. BW A868C is a selective and potent competitive prostaglandin D2 (PGD2) antagonist. BW A868C has no effect on other prostaglandin receptors (IP, EP1, EP2, TP and FP)[1]. |
Name | 7-[1-benzyl-3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxoimidazolidin-4-yl]heptanoic acid |
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Synonym | More Synonyms |
Description | BW A868C, a hydantoin compound, is a BW245C structural analogue. BW A868C is a selective and potent competitive prostaglandin D2 (PGD2) antagonist. BW A868C has no effect on other prostaglandin receptors (IP, EP1, EP2, TP and FP)[1]. |
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Related Catalog | |
Target |
PGD2 |
In Vitro | BW A868C antagonizes prosaglandin D2 and BW245C-induced activation of human platelet adenylate cyclase[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 638.1±65.0 °C at 760 mmHg |
Molecular Formula | C25H37N3O5 |
Molecular Weight | 459.578 |
Flash Point | 339.7±34.3 °C |
Exact Mass | 459.273315 |
PSA | 110.18000 |
LogP | 3.31 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.593 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Multiplexed phosphospecific flow cytometry enables large-scale signaling profiling and drug screening in blood platelets.
J. Thromb. Haemost. 12(10) , 1733-43, (2014) Dissecting the signaling events that contribute to platelet activation will increase our understanding of platelet function and aid in the development of new antiplatelet agents. However, high-through... |
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Genetic validation of a therapeutic target in a mouse model of ALS.
Sci. Transl. Med. 6(248) , 248ra104, (2014) Neurons produced from stem cells have emerged as a tool to identify new therapeutic targets for neurological diseases such as amyotrophic lateral sclerosis (ALS). However, it remains unclear to what e... |
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Pro-migratory actions of the prostacyclin receptor in human breast cancer cells that over-express cyclooxygenase-2.
Biochem. Pharmacol. 96 , 306-14, (2015) Metastasis is the major cause of death in cancer patients. Elevated expression of cyclooxygenase-2 (COX-2) is observed in many human cancers and over-production of downstream prostaglandins (PGs) has ... |
4-Imidazolidineheptanoic acid, 3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-1-(phenylmethyl)- |
BW A868C |
3-[(2-Cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-1-(phenylmethyl)- 4-imidazolidineheptanoic acid |
7-{1-Benzyl-3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-4-imidazolidinyl}heptanoic acid |
7-{1-Benzyl-3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxoimidazolidin-4-yl}heptanoic acid |