Benzophenone

Modify Date: 2024-01-02 10:51:10

Benzophenone Structure
Benzophenone structure
Common Name Benzophenone
CAS Number 119-61-9 Molecular Weight 182.218
Density 1.1±0.1 g/cm3 Boiling Point 305.4±0.0 °C at 760 mmHg
Molecular Formula C13H10O Melting Point 47-51 °C(lit.)
MSDS Chinese USA Flash Point 123.7±13.7 °C
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning

 Use of Benzophenone


Benzophenone is an endogenous metabolite.

 Names

Name Benzophenone
Synonym More Synonyms

 Benzophenone Biological Activity

Description Benzophenone is an endogenous metabolite.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 305.4±0.0 °C at 760 mmHg
Melting Point 47-51 °C(lit.)
Molecular Formula C13H10O
Molecular Weight 182.218
Flash Point 123.7±13.7 °C
Exact Mass 182.073166
PSA 17.07000
LogP 3.18
Vapour density 4.21 (vs air)
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.584
Stability Stable. Incompatible with strong oxidizing agents, strong reducing agents. Combustible.
Water Solubility insoluble (

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DI9950000
CHEMICAL NAME :
Benzophenone
CAS REGISTRY NUMBER :
119-61-9
LAST UPDATED :
199712
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C13-H10-O
MOLECULAR WEIGHT :
182.23
WISWESSER LINE NOTATION :
RVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,873,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2895 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes
REFERENCE :
EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9. Volume(issue)/page/year: 9,99,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
727 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes
REFERENCE :
EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9. Volume(issue)/page/year: 9,99,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3535 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,873,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14 gm/kg/28D-C
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 29,741,1971
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
91 gm/kg/13W-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 14,221,1994
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
109 gm/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 14,221,1994
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
75 mg/kg/15D-I
TOXIC EFFECTS :
Liver - other changes Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 50,282,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83170 No. of Facilities: 1495 (estimated) No. of Industries: 8 No. of Occupations: 11 No. of Employees: 6944 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83170 No. of Facilities: 1809 (estimated) No. of Industries: 27 No. of Occupations: 50 No. of Employees: 41516 (estimated) No. of Female Employees: 18162 (estimated)

 Safety Information

Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning
Hazard Statements H351-H410
Precautionary Statements P273-P281-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38;R50/53
Safety Phrases S26-S61-S37/39-S29-S60-S36-S62-S36/37-S33-S16-S9
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS DI9950000
Packaging Group III
Hazard Class 9
HS Code 2914399090

 Customs

HS Code 2914399090
Summary 2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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 Synonyms

Diphenylmethanone
Kayacure BP
Benzophenone
RVR
MFCD00003076
Diphenylketone
α-Oxoditane
Methanone, diphenyl-
α-Oxodiphenylmethane
A-Oxodiphenylmethane
EINECS 204-337-6
A-Oxoditane
Speedcure BP
Adjutan 6016
Mettler-Toledo Calibration substance ME 18870,Benzophenone
diphenyl ketone
Ketone, diphenyl
Benzoylbenzene
UNII-701M4TTV9O
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