Glimepiride sulfonamide

Modify Date: 2024-01-05 18:13:24

Glimepiride sulfonamide Structure
Glimepiride sulfonamide structure
Common Name Glimepiride sulfonamide
CAS Number 119018-29-0 Molecular Weight 351.421
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C16H21N3O4S Melting Point 177-179?C
MSDS N/A Flash Point N/A

 Use of Glimepiride sulfonamide


Glimepiride sulfonamide is a intermediate, and can be used to synthesize Glimepiride (HY-B0104) (antidiabetic agent)[1].

 Names

Name 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
Synonym More Synonyms

 Glimepiride sulfonamide Biological Activity

Description Glimepiride sulfonamide is a intermediate, and can be used to synthesize Glimepiride (HY-B0104) (antidiabetic agent)[1].
Related Catalog
References

[1]. Parmar HS, et al. Study on gluco-regulatory potential of glimepiride sulfonamide using in silico, in vitro and in vivo approaches. Curr Pharm Des. 2014;20(32):5212-7.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Melting Point 177-179?C
Molecular Formula C16H21N3O4S
Molecular Weight 351.421
Exact Mass 351.125275
PSA 117.95000
LogP 0.43
Index of Refraction 1.588
Storage condition Refrigerator

 Safety Information

Hazard Codes Xi
Risk Phrases R52/53
Safety Phrases 61
RIDADR NONH for all modes of transport
HS Code 2935009090

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Articles1

More Articles
Simultaneous determination of Glimepiride and Metformin hydrochloride impurities in sustained release pharmaceutical drug product by HPLC. Pawar, Shraddha, et al.

Der Pharma Chemica 2.4 , 157-168, (2010)

 Synonyms

3-Ethyl-4-methyl-2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2,5-dihydro-1H-pyrrole-1-carboxamide
SulfonamideofGlimepiride
1H-Pyrrole-1-carboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-3-ethyl-2,5-dihydro-4-methyl-2-oxo-
MFCD08460214
GliMepiride Related CoMpound B
EINECS 411-850-0
Glimepiride sulfonamide
3-Ethyl-4-methyl-2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2,5-dihydro-1H-pyrrol-1-carboxamid
4-[2-(3-ethyl-4-methyl-2-oxy-3-pyrrolinyl-1-methylamide)-ethyl]benzenesulfonamide
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