Fluorobexarotene
Modify Date: 2024-01-08 18:31:58
Fluorobexarotene structure
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Common Name | Fluorobexarotene | ||
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| CAS Number | 1190848-23-7 | Molecular Weight | 366.46800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H27FO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FluorobexaroteneFluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene[1]. |
| Name | 2-fluoro-4-(1-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)vinyl)benzoic acid |
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| Synonym | More Synonyms |
| Description | Fluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene[1]. |
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| Related Catalog | |
| Target |
RXRα:12 nM (Ki) RXRα:43 nM (EC50) |
| References |
| Molecular Formula | C24H27FO2 |
|---|---|
| Molecular Weight | 366.46800 |
| Exact Mass | 366.20000 |
| PSA | 37.30000 |
| LogP | 6.24280 |
| Fluorobexarotene |
| Teijin compound 1 |