Burixafor hydrobromide (TG-0054 hydrobromide)

Modify Date: 2024-01-13 11:14:48

Burixafor hydrobromide (TG-0054 hydrobromide) Structure
Burixafor hydrobromide (TG-0054 hydrobromide) structure
 Common Name Burixafor hydrobromide (TG-0054 hydrobromide)
CAS Number 1191450-19-7 Molecular Weight 769.01
Density N/A Boiling Point N/A
Molecular Formula C27H51N8O3P.xHBr Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Burixafor hydrobromide (TG-0054 hydrobromide)


Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization[1]. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction[2].

 Names

Name Burixafor hydrobromide

  Biological Activity

Description Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization[1]. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction[2].
Related Catalog
Target

CXCR4

References

[1]. Shelke NB, et al. Intravitreal Poly(L-lactide) Microparticles Sustain Retinal and Choroidal Delivery of TG-0054, a Hydrophilic Drug Intended for Neovascular Diseases. Drug Deliv Transl Res. 2011 Feb;1(1):76-90.

[2]. Hsu WT, et al. CXCR4 Antagonist TG-0054 Mobilizes Mesenchymal Stem Cells, Attenuates Inflammation, and Preserves Cardiac Systolic Function in a Porcine Model of Myocardial Infarction. Cell Transplant. 2015;24(7):1313-28.

 Chemical & Physical Properties

Molecular Formula C27H51N8O3P.xHBr
Molecular Weight 769.01
Storage condition 2-8℃
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Chemsrc provides CAS#:1191450-19-7 MSDS, density, melting point, boiling point, structure, etc. Its name is Burixafor hydrobromide (TG-0054 hydrobromide)>> amp version: Burixafor hydrobromide (TG-0054 hydrobromide)

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