Estradiol benzoate-d3

Modify Date: 2024-01-08 14:19:44

Estradiol benzoate-d3 Structure
Estradiol benzoate-d3 structure
Common Name Estradiol benzoate-d3
CAS Number 1192354-74-7 Molecular Weight 379.51
Density N/A Boiling Point N/A
Molecular Formula C25H25D3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Estradiol benzoate-d3


Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].

 Names

Name Estradiol benzoate-d3

 Estradiol benzoate-d3 Biological Activity

Description Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Zovko M, et al. Macromolecular prodrugs XI. Synthesis and characterization of polymer-estradiol conjugate. Int J Pharm. 2004 Nov 5;285(1-2):35-41.

[3]. García-Gómez E, et al. Role of sex steroid hormones in bacterial-host interactions. Biomed Res Int. 2013;2013:928290.

[4]. Estradiol benzoate

 Chemical & Physical Properties

Molecular Formula C25H25D3O3
Molecular Weight 379.51
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