Cruzain-IN-1

Modify Date: 2024-01-08 18:45:00

Cruzain-IN-1 Structure
Cruzain-IN-1 structure
Common Name Cruzain-IN-1
CAS Number 1199523-24-4 Molecular Weight 300.26600
Density N/A Boiling Point N/A
Molecular Formula C14H10F2N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cruzain-IN-1


Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.

 Names

Name 6-(3,6-difluorophenylamino)-9-ethyl-9H-purine-2-carbonitrile

 Cruzain-IN-1 Biological Activity

Description Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.
Related Catalog
Target

IC50:10 nM (Cruzain)[1].

References

[1]. Lee GM, et al. Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy. Biochemistry. 2012 Dec 18;51(50):10087-98.

 Chemical & Physical Properties

Molecular Formula C14H10F2N6
Molecular Weight 300.26600
Exact Mass 300.09400
PSA 79.42000
LogP 2.81268
Storage condition 2-8℃
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Price: ¥1650/10 mM * 1 mL in DMSO

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