Quinupristin

Modify Date: 2024-01-02 18:24:06

Quinupristin Structure
Quinupristin structure
Common Name Quinupristin
CAS Number 120138-50-3 Molecular Weight 1022.22000
Density 1.38g/cm3 Boiling Point N/A
Molecular Formula C53H67N9O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Quinupristin


Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2].

 Names

Name Quinupristin

 Quinupristin Biological Activity

Description Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2].
Related Catalog
In Vitro Quinupristin/dalfopristin is a combination of streptogramin antibiotics used to against infections.Quinupristin/dalfopristin targets the 23S rRNA of most Gram-positive bacteria as well as those of certain Gram-negative bacteria[1]. Quinupristin/dalfopristin is reportedly effective against Mycoplasma spp[1].
References

[1]. Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent). 2000 Jan;13(1):83-6.

[2]. Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3).

 Chemical & Physical Properties

Density 1.38g/cm3
Molecular Formula C53H67N9O10S
Molecular Weight 1022.22000
Exact Mass 1021.47000
PSA 256.50000
LogP 3.12360
Index of Refraction 1.662
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