Retro 2

Modify Date: 2024-02-05 11:51:43

Retro 2 Structure
Retro 2 structure
Common Name Retro 2
CAS Number 1201652-50-7 Molecular Weight 320.408
Density 1.2±0.1 g/cm3 Boiling Point 461.9±40.0 °C at 760 mmHg
Molecular Formula C19H16N2OS Melting Point N/A
MSDS N/A Flash Point 233.2±27.3 °C

 Use of Retro 2


Retro 2 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge.

 Names

Name 2-{(E)-[(5-Methyl-2-thienyl)methylene]amino}-N-phenylbenzamide
Synonym More Synonyms

 Retro 2 Biological Activity

Description Retro 2 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge.
References References 1. Stechmann B, et al. Cell. 2010 Apr 16;141(2):231-42. View Related Products by Target Other Targets

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 461.9±40.0 °C at 760 mmHg
Molecular Formula C19H16N2OS
Molecular Weight 320.408
Flash Point 233.2±27.3 °C
Exact Mass 320.098328
LogP 4.16
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.629

 Synonyms

2-{(E)-[(5-Methyl-2-thienyl)methylene]amino}-N-phenylbenzamide
2-{[(E)-(5-methylthiophen-2-yl)methylidene]amino}-N-phenylbenzamide
MFCD01042512
Benzamide, 2-[[(1E)-(5-methyl-2-thienyl)methylene]amino]-N-phenyl-