(2R,3R)-BOC-dolaproine

Modify Date: 2024-01-02 18:13:19

(2R,3R)-BOC-dolaproine Structure
(2R,3R)-BOC-dolaproine structure
 Common Name (2R,3R)-BOC-dolaproine
CAS Number 120205-50-7 Molecular Weight 287.352
Density 1.1±0.1 g/cm3 Boiling Point 397.8±17.0 °C at 760 mmHg
Molecular Formula C14H25NO5 Melting Point N/A
MSDS N/A Flash Point 194.4±20.9 °C

 Use of (2R,3R)-BOC-dolaproine


N-Boc-dolaproine (Dap) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].

 Names

Name (2R,3R)-3-((S)-1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid
Synonym More Synonyms

 (2R,3R)-BOC-dolaproine Biological Activity

Description N-Boc-dolaproine (Dap) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].
Related Catalog
References

[1]. Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 397.8±17.0 °C at 760 mmHg
Molecular Formula C14H25NO5
Molecular Weight 287.352
Flash Point 194.4±20.9 °C
Exact Mass 287.173279
PSA 76.07000
LogP 1.36
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.490

 Synthetic Route

 Synonyms

(2R,3R)-3-Methoxy-2-methyl-3-[(2S)-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-pyrrolidinyl]propanoic acid
2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-
(2R,3R)-3-methoxy-2-methyl-3-[(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-2-yl]propanoic acid
((2R,3R)-3-((S)-1-(tertbutoxycarbonyl)pyrrolidin-2-yl)-3-Methoxy-2-Methylpropanoic acid
Top Suppliers:I want be here

Get all suppliers and price by the below link:

(2R,3R)-BOC-dolaproine suppliers

Price: ￥950/100mg

Reference only. check more (2R,3R)-BOC-dolaproine price

Related Compounds: More...
(2R, 3R)-3-(Boc-amino)-2-methyl-3-(4-chlorophenyl)propionic acid
1217443-77-0
(2R,3R)/(2S,3S)-RACEMIC BOC-BETA-HYDROXY-PHENYLALANINE
93847-77-9
(2R,3R)-3-((TERT-BUTOXYCARBONYL)AMINO)-2-HYDROXY-4-PHENYLBUTANOIC ACID
77171-41-6
(2R,3R)-3-((TERT-BUTOXYCARBONYL)AMINO)-2-HYDROXY-3-(O-TOLYL)PROPANOIC ACID
1217716-40-9
(2R,3R)-3-((TERT-BUTOXYCARBONYL)AMINO)-2-HYDROXY-3-(P-TOLYL)PROPANOIC ACID
1217647-86-3
(2R,3R)-3-[(2S)-1-[(tert-butoxy)carbonyl]pyrrolidin-2-yl]-3-hydroxy-2-methylpropanoic acid
133565-38-5
(2R,3R)-3-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-2-HYDROXY-3-(O-TOLYL)PROPANOIC ACID
1217724-38-3
(2R,3R)-3-Methylpent-4-en-2-ol
74080-50-5
(2R,3R)-3-(((S)-1-phenylbut-3-en-1-yl)oxy)butan-2-ol
83862-16-2
N-methyl-N-{1-[6-methyl-2-(methylsulfanyl)pyrimidin-4-yl]piperidin-4-yl}cyclopropanesulfonamide
2741924-77-4
(3R)-3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]-4-methylpentanoic acid
2171352-17-1
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
tert-Butyl-DL-alanine
1375289-11-4
Chemsrc provides (2R,3R)-BOC-dolaproine(CAS#:120205-50-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of (2R,3R)-BOC-dolaproine are included as well.>> amp version: (2R,3R)-BOC-dolaproine

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved