HNMPA-(AM)3

Modify Date: 2024-03-02 16:35:02

HNMPA-(AM)3 Structure
HNMPA-(AM)3 structure
Common Name HNMPA-(AM)3
CAS Number 120944-03-8 Molecular Weight 454.364
Density 1.3±0.1 g/cm3 Boiling Point 573.1±50.0 °C at 760 mmHg
Molecular Formula C20H23O10P Melting Point N/A
MSDS N/A Flash Point 313.2±50.4 °C

 Use of HNMPA-(AM)3


HNMPA-(AM)3 is a cell-permeable and selective insulin receptor tyrosine kinase inhibitor analog of HNMPA. HNMPA-(AM)3 greatly inhibits the ability of prothoracicotropic hormone (PTTH) to activate ERK phosphorylation and stimulate ecdysteroidogenesis[1].

 Names

Name hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester
Synonym More Synonyms

 HNMPA-(AM)3 Biological Activity

Description HNMPA-(AM)3 is a cell-permeable and selective insulin receptor tyrosine kinase inhibitor analog of HNMPA. HNMPA-(AM)3 greatly inhibits the ability of prothoracicotropic hormone (PTTH) to activate ERK phosphorylation and stimulate ecdysteroidogenesis[1].
Related Catalog
References

[1]. Gu SH, et al. PTTH-stimulated ERK phosphorylation in prothoracic glands of the silkworm, Bombyx mori: role of Ca2+/calmodulin and receptor tyrosine kinase. J Insect Physiol. 2010;56(1):93-101.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 573.1±50.0 °C at 760 mmHg
Molecular Formula C20H23O10P
Molecular Weight 454.364
Flash Point 313.2±50.4 °C
Exact Mass 454.102875
LogP 4.41
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.543

 Synonyms

Phosphonic acid, P-[[(acetyloxy)methoxy]-2-naphthalenylmethyl]-, bis[(acetyloxy)methyl] ester
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester
3-(Acetoxymethoxy)-4-(2-naphthyl)-3-oxido-8-oxo-2,5,7-trioxa-3λ5-phosphanon-1-yl acetate
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