Bumetanide D5

Modify Date: 2024-01-03 18:24:59

Bumetanide D5 Structure
Bumetanide D5 structure
Common Name Bumetanide D5
CAS Number 1216739-35-3 Molecular Weight 369.44700
Density N/A Boiling Point N/A
Molecular Formula C17H15D5N2O5S Melting Point 234-236 °C
MSDS N/A Flash Point N/A

 Use of Bumetanide D5


Bumetanide D5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with  IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1].

 Names

Name 3-(butylamino)-4-(2,3,4,5,6-pentadeuteriophenoxy)-5-sulfamoylbenzoic acid
Synonym More Synonyms

 Bumetanide D5 Biological Activity

Description Bumetanide D5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with  IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1].
Related Catalog
References

[1]. Sandström PE1, et al. Evidence for diabetogenic action of bumetanide in mice.Eur J Pharmacol. 1988 May 20;150(1-2):35-41.

 Chemical & Physical Properties

Melting Point 234-236 °C
Molecular Formula C17H15D5N2O5S
Molecular Weight 369.44700
Exact Mass 369.14100
PSA 127.10000
LogP 4.89060

 Safety Information

Hazard Codes Xi

 Synonyms

Fordiuran-d5
[2H5]-Bumetanide
Bumex-d5
Bufenox-d5
Burinex-d5
PF 1593-d5
Lunetoron-d5
Lixil-d5
Bumetanide-d5