Fluo-3AM

Modify Date: 2024-01-02 10:08:13

Fluo-3AM Structure
Fluo-3AM structure
Common Name Fluo-3AM
CAS Number 121714-22-5 Molecular Weight 1129.85
Density 1.5±0.1 g/cm3 Boiling Point 1075.8±65.0 °C at 760 mmHg
Molecular Formula C51H50Cl2N2O23 Melting Point N/A
MSDS Chinese USA Flash Point 604.4±34.3 °C

 Use of Fluo-3AM


Fluo-3AM(Fluo-3-pentaacetoxymethyl ester) is a calcium indicator that exhibit an increase in fluorescence upon binding Ca2+; used to image the spatial dynamics of Ca2+ signaling, in flow cytometry experiments involving photoactivation of caged chelators, second messengers, and neurotransmitters, and for cell-based pharmacological screening.

 Names

Name acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-(2,7-dichloro-3-hydroxy-6-oxoxanthen-9-yl)phenoxy]ethoxy]-4-methylanilino]acetate
Synonym More Synonyms

 Fluo-3AM Biological Activity

Description Fluo-3AM(Fluo-3-pentaacetoxymethyl ester) is a calcium indicator that exhibit an increase in fluorescence upon binding Ca2+; used to image the spatial dynamics of Ca2+ signaling, in flow cytometry experiments involving photoactivation of caged chelators, second messengers, and neurotransmitters, and for cell-based pharmacological screening.
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 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 1075.8±65.0 °C at 760 mmHg
Molecular Formula C51H50Cl2N2O23
Molecular Weight 1129.85
Flash Point 604.4±34.3 °C
PSA 285.78000
LogP 5.40
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.631
Storage condition −20°C
Water Solubility DMSO: soluble

 Safety Information

Hazard Codes Xi
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles1

More Articles
Role of dopamine D2 receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes.

J. Biomed. Sci. 18 , 18, (2011)

Myocardial ischemia/reperfusion injury is the major cause of morbidity and mortality for cardiovascular diseases. Dopamine D2 receptors are expressed in cardiac tissues. However, the roles of dopamine...

 Synonyms

Acetoxymethyl {[2-(acetoxymethoxy)-2-oxoethyl](2-{2-[2-{bis[2-(acetoxymethoxy)-2-oxoethyl]amino}-5-(2,7-dichloro-6-hydroxy-3-oxo-3H-xanthen-9-yl)phenoxy]ethoxy}-4-methylphenyl)amino}acetate
4-(6-Acetoxymethoxy-2,7-dichloro-3-oxo-9-xanthenyl)-4'-methyl-2,2'(ethylenedioxy)dianiline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester
MFCD00083336
Fluo 3-AM
Fluo-3AM
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