A 350619 hydrochloride

Modify Date: 2024-07-30 13:56:55

A 350619 hydrochloride Structure
A 350619 hydrochloride structure
 Common Name A 350619 hydrochloride
CAS Number 1217201-17-6 Molecular Weight 425.41
Density N/A Boiling Point N/A
Molecular Formula C21H26Cl2N2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A 350619 hydrochloride


A-350619 hydrochloride is a soluble guanylate cyclase (sGC) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction[1][2].

 Names

Name (2E)-3-{2-[(4-Chlorophenyl)sulfanyl]phenyl}-N-[4-(dimethylamino)butyl]acrylamide hydrochloride (1:1)
Synonym More Synonyms

 A 350619 hydrochloride Biological Activity

Description A-350619 hydrochloride is a soluble guanylate cyclase (sGC) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction[1][2].
Related Catalog
Target

sGC[1][2].

References

[1]. Kotzki S, et al. Anodal iontophoresis of a soluble guanylate cyclase stimulator induces a sustained increase in skin blood flow in rats. J Pharmacol Exp Ther. 2013 Sep;346(3):424-31.  

[2]. Miller LN, et al. A-350619: a novel activator of soluble guanylyl cyclase. Life Sci. 2003 Jan 17;72(9):1015-25.  

 Chemical & Physical Properties

Molecular Formula C21H26Cl2N2OS
Molecular Weight 425.41
Exact Mass 424.114288

 Synonyms

2-Propenamide, 3-[2-[(4-chlorophenyl)thio]phenyl]-N-[4-(dimethylamino)butyl]-, (2E)-, hydrochloride (1:1)
(2E)-3-{2-[(4-Chlorophenyl)sulfanyl]phenyl}-N-[4-(dimethylamino)butyl]acrylamide hydrochloride (1:1)
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