Trimyristin--d15

Modify Date: 2024-02-21 00:27:02

Trimyristin--d15 Structure
Trimyristin--d15 structure
Common Name Trimyristin--d15
CAS Number 1219804-94-0 Molecular Weight 738.25
Density N/A Boiling Point N/A
Molecular Formula C45H71D15O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Trimyristin--d15


Trimyristin--d15 is the deuterium labeled Trimyristin. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1].

 Names

Name Trimyristin--d15

 Trimyristin--d15 Biological Activity

Description Trimyristin--d15 is the deuterium labeled Trimyristin. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Jaiswal P, et al. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the NervousTissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746.

 Chemical & Physical Properties

Molecular Formula C45H71D15O6
Molecular Weight 738.25