AG 99

Modify Date: 2024-01-02 12:29:16

AG 99 Structure
AG 99 structure
Common Name AG 99
CAS Number 122520-85-8 Molecular Weight 204.182
Density 1.5±0.1 g/cm3 Boiling Point 544.4±50.0 °C at 760 mmHg
Molecular Formula C10H8N2O3 Melting Point 231 °C
MSDS N/A Flash Point 283.0±30.1 °C

 Use of AG 99


(E)-AG 99 ((E)-Tyrphostin 46; (E)-Tyrphostin AG 99) is a potent EGFR inhibitor[1].

 Names

Name 2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 544.4±50.0 °C at 760 mmHg
Melting Point 231 °C
Molecular Formula C10H8N2O3
Molecular Weight 204.182
Flash Point 283.0±30.1 °C
Exact Mass 204.053497
PSA 107.34000
LogP 0.02
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.711
Storage condition Desiccate at +4°C

 Synthetic Route

~71%

AG 99 Structure

AG 99

CAS#:122520-85-8

Literature: Yissum Research Development Company of the Hebrew University of Jerusalem Patent: US5217999 A1, 1993 ; US 5217999 A

~69%

AG 99 Structure

AG 99

CAS#:122520-85-8

Literature: Hussoin; FitzGerald; Wick Journal of Pharmaceutical Sciences, 1991 , vol. 80, # 5 p. 416 - 418

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AG 99 Structure

AG 99

CAS#:122520-85-8

Literature: Rosenmund; Boehm Justus Liebigs Annalen der Chemie, 1924 , vol. 437, p. 143

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AG 99 Structure

AG 99

CAS#:122520-85-8

Literature: Piccinini Chem. Zentralbl., 1904 , vol. 75, # II p. 903

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AG 99 Structure

AG 99

CAS#:122520-85-8

Literature: Rosenmund; Boehm Justus Liebigs Annalen der Chemie, 1924 , vol. 437, p. 143

 Synonyms

3,4-dihydroxybenzalcyanoacetamide
IN1036
Tyrphostin A46
2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)-
(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)acrylamide
Tyrphostin AG 99
HMS3266G04
(E)-2-Cyano-3-(3,4-Dihydroxyphenyl)Prop-2-Enamide
(E)-AG 99
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Price: ¥1210/10 mM * 1 mL in DMSO

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