2′-Deoxy-N-(2-furanylmethyl)guanosine

Modify Date: 2024-01-13 13:42:50

2′-Deoxy-N-(2-furanylmethyl)guanosine Structure
2′-Deoxy-N-(2-furanylmethyl)guanosine structure
Common Name 2′-Deoxy-N-(2-furanylmethyl)guanosine
CAS Number 1227069-12-6 Molecular Weight 347.33
Density 1.8±0.1 g/cm3 Boiling Point N/A
Molecular Formula C15H17N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2′-Deoxy-N-(2-furanylmethyl)guanosine


2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

 Names

Name 2'-Deoxy-N-(2-furylmethyl)guanosine
Synonym More Synonyms

 2′-Deoxy-N-(2-furanylmethyl)guanosine Biological Activity

Description 2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Molecular Formula C15H17N5O5
Molecular Weight 347.33
Exact Mass 347.122955
LogP -1.79
Index of Refraction 1.798

 Synonyms

2'-Deoxy-N-(2-furylmethyl)guanosine
Guanosine, 2'-deoxy-N-(2-furanylmethyl)-
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