Balovaptan structure
|
Common Name | Balovaptan | ||
---|---|---|---|---|
CAS Number | 1228088-30-9 | Molecular Weight | 409.912 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 597.0±60.0 °C at 760 mmHg | |
Molecular Formula | C22H24ClN5O | Melting Point | N/A | |
MSDS | N/A | Flash Point | 314.9±32.9 °C |
Use of BalovaptanBalovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism. |
Name | balovaptan |
---|---|
Synonym | More Synonyms |
Description | Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism. |
---|---|
Related Catalog | |
Target |
Ki: 1 nM (hV1a), 39 nM (mV1a)[1] |
In Vitro | Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for hV1a and mhV1a, and is used for the research of autism. Balovaptan shows >30000-fold selectivity for hV1a over hV2 receptors, 9891-fold selectivity over hOTR (human oxytocin receptor)[1]. |
References |
Density | 1.4±0.1 g/cm3 |
---|---|
Boiling Point | 597.0±60.0 °C at 760 mmHg |
Molecular Formula | C22H24ClN5O |
Molecular Weight | 409.912 |
Flash Point | 314.9±32.9 °C |
Exact Mass | 409.166931 |
LogP | 3.16 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.702 |
4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine, 8-chloro-5,6-dihydro-5-methyl-1-[trans-4-(2-pyridinyloxy)cyclohexyl]- |
RAX5D5AGV6 |
8-Chloro-5-methyl-1-[trans-4-(2-pyridinyloxy)cyclohexyl]-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine |
10298 |
balovaptan |