Methyl propionate-PEG12

Modify Date: 2024-01-18 23:55:50

Methyl propionate-PEG12 Structure
Methyl propionate-PEG12 structure
Common Name Methyl propionate-PEG12
CAS Number 1239588-11-4 Molecular Weight 632.735
Density 1.1±0.1 g/cm3 Boiling Point 646.1±50.0 °C at 760 mmHg
Molecular Formula C28H56O15 Melting Point N/A
MSDS N/A Flash Point 190.2±23.6 °C

 Use of Methyl propionate-PEG12


Methyl propionate-PEG12 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG13-acid
Synonym More Synonyms

 Methyl propionate-PEG12 Biological Activity

Description Methyl propionate-PEG12 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 646.1±50.0 °C at 760 mmHg
Molecular Formula C28H56O15
Molecular Weight 632.735
Flash Point 190.2±23.6 °C
Exact Mass 632.361938
LogP -4.47
Vapour Pressure 0.0±4.4 mmHg at 25°C
Index of Refraction 1.461

 Synonyms

Methyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oate
3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacontan-39-oic acid, 1-hydroxy-, methyl ester