Soluble epoxide hydrolase inhibitor
Modify Date: 2024-01-04 20:06:10
Soluble epoxide hydrolase inhibitor structure
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Common Name | Soluble epoxide hydrolase inhibitor | ||
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| CAS Number | 1241826-88-9 | Molecular Weight | 441.31 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H12F5N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Soluble epoxide hydrolase inhibitorSoluble epoxide hydrolase inhibitor is an inhibitor of soluble epoxide hydrolase, and inhibits human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4, extracted from patent WO 2010096722 A1, example 57. |
| Name | Soluble epoxide hydrolase inhibitor |
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| Description | Soluble epoxide hydrolase inhibitor is an inhibitor of soluble epoxide hydrolase, and inhibits human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4, extracted from patent WO 2010096722 A1, example 57. |
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| Related Catalog | |
| Target |
pIC50: 8.4 (h-sEH)[1] |
| In Vitro | Soluble epoxide hydrolase inhibitor (Example 57) is an inhibitor of soluble epoxide hydrolase, and inhibits human soluble epoxide hydrolase with pIC50 of 8.4[1]. |
| Kinase Assay | The sEH inhibitory properties of test compounds (including Soluble epoxide hydrolase inhibitor) are determined using a black 384-well-plate format under the following reaction conditions: 20 mM Tris pH 7.0, 0.1 mM EDTA, 0.1 mg/mL BSA, 5 μM PHOME (substrate), 2 nM sEH enzyme, 1% DMSO (from test compound). Reaction product is determined quantitatively by fluorescence intensity using a Fluorescence plate reader with an excitation wavelength at 330 nm and emission at 465 nm[1]. |
| References |
| Molecular Formula | C18H12F5N5O3 |
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| Molecular Weight | 441.31 |