SPI-112Me

Modify Date: 2024-09-07 14:28:29

SPI-112Me Structure
SPI-112Me structure
Common Name SPI-112Me
CAS Number 1243685-62-2 Molecular Weight 482.484
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C23H19FN4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SPI-112Me


SPI-112Me is a prodrug for SPI-112, which preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by a factor of 20 in cell-free assays.

 Names

Name SPI-112Me
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C23H19FN4O5S
Molecular Weight 482.484
Exact Mass 482.106018
LogP 3.86
Index of Refraction 1.667
Storage condition -20℃

 Synonyms

Benzoic acid, 3-[(2Z)-2-[5-[[[(4-fluorophenyl)methyl]amino]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]hydrazinyl]-, methyl ester
Methyl 3-[(2Z)-2-{5-[(4-fluorobenzyl)sulfamoyl]-2-oxo-1,2-dihydro-3H-indol-3-ylidene}hydrazino]benzoate
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