Meclizine D8

Modify Date: 2024-01-10 13:58:30

Meclizine D8 structure	Common Name	Meclizine D8
	CAS Number	1246816-06-7	Molecular Weight	399.00
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₁₉D₈ClN₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Meclizine D8

Meclizine D8 (Meclozine D8) is a deuterium labeled Meclizine. Meclizine is a histamine H1 receptor antagonist and has the potential to treat nausea and motion sickness. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR[1][2][3].

Name	Meclizine D8

Description	Meclizine D8 (Meclozine D8) is a deuterium labeled Meclizine. Meclizine is a histamine H1 receptor antagonist and has the potential to treat nausea and motion sickness. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	Histamine H1 Receptor.
References	[1]. King, C.T., S.A. Weaver, and S.A. Narrod, Antihistamines and Teratogenicity in the Rat. J Pharmacol Exp Ther, 1965. 147: p. 391-8. [2]. Huang, W., et al., Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR. Mol Endocrinol, 2004. 18(10): p. 2402-8. [3]. Wendong Huang, et al. Meclizine Is an Agonist Ligand for Mouse Constitutive Androstane Receptor (CAR) and an Inverse Agonist for Human CAR.

Molecular Formula	C₂₅H₁₉D₈ClN₂
Molecular Weight	399.00

Meclizine D8

Use of Meclizine D8

Names

Meclizine D8 Biological Activity

Chemical & Physical Properties