Cortodoxone-d5

Modify Date: 2024-01-09 16:09:30

Cortodoxone-d5 Structure
Cortodoxone-d5 structure
Common Name Cortodoxone-d5
CAS Number 1258063-56-7 Molecular Weight 351.491
Density 1.2±0.1 g/cm3 Boiling Point 524.5±50.0 °C at 760 mmHg
Molecular Formula C21H25D5O4 Melting Point 208 °C (dec.)
MSDS N/A Flash Point 285.1±26.6 °C

 Use of Cortodoxone-d5


Cortodoxone-d5 (11-Deoxycortisol-d5) is the deuterium labeled Cortodoxone.

 Names

Name 11-Deoxycortisol-[D5]
Synonym More Synonyms

 Cortodoxone-d5 Biological Activity

Description Cortodoxone-d5 (11-Deoxycortisol-d5) is the deuterium labeled Cortodoxone.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 524.5±50.0 °C at 760 mmHg
Melting Point 208 °C (dec.)
Molecular Formula C21H25D5O4
Molecular Weight 351.491
Flash Point 285.1±26.6 °C
Exact Mass 351.245789
LogP 2.74
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.578
Storage condition 20°C

 Safety Information

RIDADR NONH for all modes of transport

 Articles1

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An LC-MS/MS method for steroid profiling during adrenal venous sampling for investigation of primary aldosteronism.

J. Steroid Biochem. Mol. Biol. 145 , 75-84, (2015)

Steroid profiling for diagnosis of endocrine disorders featuring disordered production of steroid hormones is now possible from advances in liquid chromatography with tandem mass spectrometry (LC-MS/M...

 Synonyms

Cortexolone-2,2,4,6,6-d5
11-DEOXYCORTISOL-2,2,4,6,6-D5
17,21-Dihydroxy(2,2,4,6,6-2H5)pregn-4-ene-3,20-dione
Reichstein's substance S (2,2,4,6,6-d5)
Cortodoxone-D5 (2,2,4,6,6-D5)
EINECS 200-659-6
11-Deoxy-17-hydroxycorticosterone-2,2,4,6,6-d5
Pregn-4-ene-3,20-dione-2,2,4,6,6-d5, 17,21-dihydroxy-
17,21-Dihydroxyprogesterone-2,2,4,6,6-d5
11-Deoxycortisol-D5 (2,2,4,6,6-D5) solution
11-Desoxycortisol-D5 (2,2,4,6,6-D5)
11-Deoxycortisol-D5 (2,2,4,6,6-D5)
MFCD15144809