PHCCC(4Me)

Modify Date: 2024-01-20 16:34:42

PHCCC(4Me) structure	Common Name	PHCCC(4Me)
	CAS Number	1259532-01-8	Molecular Weight	308.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₆N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PHCCC(4Me)

PHCCC(4Me) (THCCC), a PHCCC analog, is a dual mGluR2 (IC50 of 1.5 μM) negative allosteric modulator and mGluR3 (EC50 of 8.9 μM) positive allosteric modulator[1].

Name	PHCCC(4Me)

Description	PHCCC(4Me) (THCCC), a PHCCC analog, is a dual mGluR2 (IC50 of 1.5 μM) negative allosteric modulator and mGluR3 (EC50 of 8.9 μM) positive allosteric modulator[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
In Vitro	PHCCC(4Me) (THCCC; Compound 3) shows micromolar affinityfor mGluR2, with a Ki value of 0.6 μM[1].
References	[1]. Stephan Schann, et al. Chemical switch of a metabotropic glutamate receptor 2 silent allosteric modulator into dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulators. J Med Chem. 2010 Dec 23;53(24):8775-9.

Molecular Formula	C₁₈H₁₆N₂O₃
Molecular Weight	308.33

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PHCCC(4Me)
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: PHCCC(4Me)
Price: $Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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