QWF

Modify Date: 2024-01-10 11:55:31

QWF Structure
QWF structure
Common Name QWF
CAS Number 126088-82-2 Molecular Weight 697.78
Density 1.26g/cm3 Boiling Point N/A
Molecular Formula C38H43N5O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of QWF


QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM[1].

 Names

Name benzyl (2S)-2-[[(2R)-2-[[(2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoyl]amino]-3-(1-formylindol-3-yl)propanoyl]amino]-3-phenylpropanoate
Synonym More Synonyms

 QWF Biological Activity

Description QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM[1].
Related Catalog
Target

IC50: 0.09 μM (substance P)[1]

References

[1]. Hagiwara D, et al. Studies on neurokinin antagonists. 1. The design of novel tripeptides possessing the glutaminyl-D-tryptophylphenylalanine sequence as substance P antagonists. J Med Chem. 1992 May 29;35(11):2015-25.  

 Chemical & Physical Properties

Density 1.26g/cm3
Molecular Formula C38H43N5O8
Molecular Weight 697.78
Exact Mass 697.31100
PSA 199.38000
LogP 6.97340
Index of Refraction 1.609

 Synonyms

(R)-2-Amino-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoic acid
BOC-D-tryptophan
Boc-Gln-D-Trp(CHO)-Phe-OBzl
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