Propofol-d17
Modify Date: 2024-01-10 12:18:21
Propofol-d17 structure
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Common Name | Propofol-d17 | ||
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| CAS Number | 1261393-54-7 | Molecular Weight | 195.376 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 256.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C12HD17O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 107.5±7.2 °C | |
Use of Propofol-d17Propofol-d17 (2,6-Diisopropylphenol-d17) is the deuterium labeled Propofol. Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic[1]. |
| Name | 2,6-Bis[(2H7)-2-propanyl](2H3)phenol |
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| Synonym | More Synonyms |
| Description | Propofol-d17 (2,6-Diisopropylphenol-d17) is the deuterium labeled Propofol. Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic[1]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 256.0±0.0 °C at 760 mmHg |
| Molecular Formula | C12HD17O |
| Molecular Weight | 195.376 |
| Flash Point | 107.5±7.2 °C |
| Exact Mass | 195.242477 |
| LogP | 4.16 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.513 |
| 2,6-Bis[(2H7)-2-propanyl](2H3)phenol |
| Phenol-3,4,5-d3, 2,6-bis[1-(methyl-d3)ethyl-1,2,2,2-d4]- |