Tilifodiolide

Modify Date: 2024-01-10 21:11:06

Tilifodiolide Structure
Tilifodiolide structure
Common Name Tilifodiolide
CAS Number 126724-95-6 Molecular Weight 336.34
Density 1.4±0.1 g/cm3 Boiling Point 577.3±50.0 °C at 760 mmHg
Molecular Formula C20H16O5 Melting Point N/A
MSDS N/A Flash Point 303.0±30.1 °C

 Use of Tilifodiolide


Tilifodiolide ((-)-Tilifodiolide) is a lactone, which can be isolated from the roots of Salvia tiliaefolia. Tilifodiolide has anti-inflammatory activity in mice model[1].

 Names

Name (1R,8S)-1-(furan-3-yl)-8-(5-oxo-2H-furan-4-yl)-6,7,8,9-tetrahydro-1H-benzo[e][2]benzofuran-3-one
Synonym More Synonyms

 Tilifodiolide Biological Activity

Description Tilifodiolide ((-)-Tilifodiolide) is a lactone, which can be isolated from the roots of Salvia tiliaefolia. Tilifodiolide has anti-inflammatory activity in mice model[1].
Related Catalog
In Vitro Tilifodiolide (200 mg/kg; single dose) shows anti-inflammatory activity in vivo in acetic acid induced-writhing mouse model[1].
References

[1]. González-Chávez MM, Alonso-Castro AJ, Zapata-Morales JR, Arana-Argáez V, Torres-Romero JC, Medina-Rivera YE, Sánchez-Mendoza E, Pérez-Gutiérrez S. Anti-inflammatory and antinociceptive effects of tilifodiolide, isolated from Salvia tiliifolia Vahl (Lamiaceae). Drug Dev Res. 2018 Jun;79(4):165-172.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 577.3±50.0 °C at 760 mmHg
Molecular Formula C20H16O5
Molecular Weight 336.34
Flash Point 303.0±30.1 °C
Exact Mass 336.099762
PSA 65.74000
LogP 1.93
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.641

 Safety Information

Hazard Codes Xi

 Synonyms

Naphtho[1,2-c]furan-3(1H)-one, 8-(2,5-dihydro-2-oxo-3-furanyl)-1-(3-furanyl)-6,7,8,9-tetrahydro-, (1R,8S)-
Tilifodiolide
(1R,8S)-1-(3-Furyl)-8-(2-oxo-2,5-dihydro-3-furanyl)-6,7,8,9-tetrahydronaphtho[1,2-c]furan-3(1H)-one