MK 1903

Modify Date: 2024-01-14 08:35:27

MK 1903 Structure
MK 1903 structure
Common Name MK 1903
CAS Number 1268882-43-4 Molecular Weight 164.161
Density 1.6±0.1 g/cm3 Boiling Point 438.1±45.0 °C at 760 mmHg
Molecular Formula C8H8N2O2 Melting Point N/A
MSDS N/A Flash Point 218.7±28.7 °C

 Use of MK 1903


MK-1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist[1].

 Names

Name mk-1903
Synonym More Synonyms

 MK 1903 Biological Activity

Description MK-1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist[1].
Related Catalog
References

[1]. Boatman PD, et al. (1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humans. J Med Chem. 2012 Apr 26;55(8):3644-66.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 438.1±45.0 °C at 760 mmHg
Molecular Formula C8H8N2O2
Molecular Weight 164.161
Flash Point 218.7±28.7 °C
Exact Mass 164.058578
LogP 0.77
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.732
Storage condition Store at -20°C
Water Solubility Soluble in DMSO > 10 mM

 Synonyms

1H-Cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid, 4,4a,5,5a-tetrahydro-, (4aR,5aR)-
mk-1903
MFCD11973801
MFCD27991272
(4aR,5aR)-4,4a,5,5a-Tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid