NSI-189

Modify Date: 2024-01-09 17:09:36

NSI-189 Structure
NSI-189 structure
Common Name NSI-189
CAS Number 1270138-40-3 Molecular Weight 366.500
Density 1.1±0.1 g/cm3 Boiling Point 534.7±50.0 °C at 760 mmHg
Molecular Formula C22H30N4O Melting Point N/A
MSDS N/A Flash Point 277.2±30.1 °C

 Use of NSI-189


NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.IC50 value:Target: in vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].in vivo: NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20% [3].

 Names

Name (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone
Synonym More Synonyms

 NSI-189 Biological Activity

Description NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.IC50 value:Target: in vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].in vivo: NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20% [3].
Related Catalog
References

[1]. http://gizmodo.com/5874433/the-pill-that-could-cure-depression-by-growing-your-brain

[2]. Compositions to effect neuronal growth US 8030492 B2

[3]. Why Neuralstem Could Provide A 10x Return

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 534.7±50.0 °C at 760 mmHg
Molecular Formula C22H30N4O
Molecular Weight 366.500
Flash Point 277.2±30.1 °C
Exact Mass 366.241974
PSA 48.47000
LogP 4.13
Appearance of Characters white solid
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.601
Storage condition -20℃

 Synonyms

(4-Benzyl-1-piperazinyl){2-[(3-methylbutyl)amino]-3-pyridinyl}methanone
Methanone, [2-[(3-methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]-
unii-yve9u408zl
UNII:YVE9U408ZL
NSI-189
NSI189
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Price: ¥818/10 mM * 1 mL in DMSO

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