(β-Ala8)-Neurokinin A (4-10) structure
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Common Name | (β-Ala8)-Neurokinin A (4-10) | ||
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CAS Number | 127633-71-0 | Molecular Weight | 764.93200 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C35H56N8O9S | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Use of (β-Ala8)-Neurokinin A (4-10)(β-Ala8)-Neurokinin A (4-10), a neuropeptide, is a potent and selective NK-2 tachykinin receptor (Neurokinin Receptor) agonist[1]. |
Name | 3-amino-4-[[1-[[1-[[1-[[3-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-3-oxopropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid |
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Synonym | More Synonyms |
Description | (β-Ala8)-Neurokinin A (4-10), a neuropeptide, is a potent and selective NK-2 tachykinin receptor (Neurokinin Receptor) agonist[1]. |
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Related Catalog | |
In Vivo | (β-Ala8)-Neurokinin A (4-10) (2 μg/kg; i.v.) increases colonic tone in conscious female dogs[2]. |
References |
Molecular Formula | C35H56N8O9S |
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Molecular Weight | 764.93200 |
Exact Mass | 764.38900 |
PSA | 306.31000 |
LogP | 2.66780 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
Analogs of neurokinin A(4-10) afford protection against gastroduodenal ulcers in rats.
Peptides 11 , 293-297, (1990) We have developed a novel series of peptides, related to the NKA(4-10) sequence, in which substitution of selected amino acids determined variations in the affinity for the TK receptor subtypes. Subcu... |
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Tachykinin-induced responses via neurokinin-1 and -3 receptors in hamster submandibular ganglion neurones.
Arch. Oral Biol. 44 , 455-463, (1999) Both substance P and neurokinin A are known as neurotransmitters of the submandibular ganglion cell. In this study, the effects of neurokinin (NK) receptor-subtype agonists on hamster submandibular ga... |
Asp-Ala-Phe-Val-|A-Ala-Leu-Met-NH2 |
[Ala5,|A-Ala8]-|A-Neurokinin Fragment 4-10 |