C-Type Natriuretic Peptide (32-53) (human, porcine, rat) acetate salt

Modify Date: 2024-01-02 19:45:13

C-Type Natriuretic Peptide (32-53) (human, porcine, rat) acetate salt structure	Common Name	C-Type Natriuretic Peptide (32-53) (human, porcine, rat) acetate salt
	CAS Number	127869-51-6	Molecular Weight	2197.60000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉₃H₁₅₇N₂₇O₂₈S₃	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of C-Type Natriuretic Peptide (32-53) (human, porcine, rat) acetate salt

C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. C-type natriuretic peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone.

Name	Natriuretic peptide, C-type
Synonym	More Synonyms

Description	C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. C-type natriuretic peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Research Areas >> Cardiovascular Disease Peptides
In Vitro	C-Type Natriuretic Peptide (CNP) has been shown to be present in the central nervous system of mammals and to participate in the regulation of the homeostasis of the fluid, electrolytic balance and blood pressure, learning and memory[1].
In Vivo	I.c.v. administration of C-Type Natriuretic Peptide (CNP) (1-22) in a dose of 2 nM induces an increase in the severity of picrotoxin-kindled convulsions 24 and 48 hrs after application of the peptide[1].
Animal Admin	Rats[1] Rats are preliminarily kindled with picrotoxin and convulsion is monitored. Rats then receive I.c.v. administration of C-Type Natriuretic Peptide (CNP) (1-22) (0.2, 1 or 2 nM in 2 mcl of 0.9% NaCI) under conditions of free behavior. Control animals receive an equal volume of saline. Within 10 min after the injections of the peptides, picrotoxin (1.5 mg/kg) is administered i.p. and the convulsion severity is evaluated as mentioned above[1].
References	[1]. Mazarati AM, et al. ANP(1-28), BNP(1-32) and CNP(1-22) increase the severity of picrotoxin-kindled seizure syndrome in rats. Life Sci. 1993;52(3):PL19-24.

Molecular Formula	C₉₃H₁₅₇N₂₇O₂₈S₃
Molecular Weight	2197.60000
Exact Mass	2196.09000
PSA	962.25000
LogP	0.46880
Storage condition	-20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3.0

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Dihydrexidine hydrochloride

MFCD00080348

C-Type natriuretic peptide

GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS(DISULFIDE BRIDGE:CYS6-CYS22)

NATRIURETIC PEPTIDE,C-TYPE

CNP

GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS: GLSKGCFGLKLDRIGSMSGLGCDISULFIDE BRIDGE CYS6-CYS22

C-Type Natriuretic Peptide (CNP) (1-22), human