2-PCCA
Modify Date: 2022-11-21 17:42:28
2-PCCA structure
|
Common Name | 2-PCCA | ||
|---|---|---|---|---|
| CAS Number | 1287205-42-8 | Molecular Weight | 455.634 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 623.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C30H37N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 330.8±31.5 °C | |
Use of 2-PCCAA potent, selective agonist of the orphan GPR88 receptor with EC50 of 877 nM; inhibits isoproterenol-stimulated cAMP accumulation in a concentration-dependent manner in cells expressing GPR88 through a Gαi-coupled pathway; dose-dependently decreases the locomotor activity in rats at 0.1-3.2mg/kg, also decreases methamphetamine-induced hyperactivity combined with methamphetamine; does not alter the behavioral effects of methamphetamine in rats alone. |
| Name | compound 2 [PMID: 24793972] |
|---|---|
| Synonym | More Synonyms |
| Description | A potent, selective agonist of the orphan GPR88 receptor with EC50 of 877 nM; inhibits isoproterenol-stimulated cAMP accumulation in a concentration-dependent manner in cells expressing GPR88 through a Gαi-coupled pathway; dose-dependently decreases the locomotor activity in rats at 0.1-3.2mg/kg, also decreases methamphetamine-induced hyperactivity combined with methamphetamine; does not alter the behavioral effects of methamphetamine in rats alone. |
|---|---|
| References | References 1. Li JX, et al. Eur J Pharmacol. 2013 Jan 5;698(1-3):272-7. 2. Jin C, et al. ACS Chem Neurosci. 2014 Jul 16;5(7):576-87. 3. Jin C, et al. ACS Chem Neurosci. 2016 Oct 19;7(10):1418-1432. View Related Products by Target GPR88 |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 623.4±55.0 °C at 760 mmHg |
| Molecular Formula | C30H37N3O |
| Molecular Weight | 455.634 |
| Flash Point | 330.8±31.5 °C |
| Exact Mass | 455.293671 |
| LogP | 5.61 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.601 |
| Cyclopropanecarboxamide, N-[(2S,3S)-2-amino-3-methylpentyl]-N-(4'-propyl[1,1'-biphenyl]-4-yl)-2-(2-pyridinyl)-, (1R,2R)- |
| compound 2 [PMID: 24793972] |
| (1R,2R)-N-[(2S,3S)-2-Amino-3-methylpentyl]-N-(4'-propyl-4-biphenylyl)-2-(2-pyridinyl)cyclopropanecarboxamide |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 2-PCCA
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: 2-PCCA
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: 2-PCCA
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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